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Non-Surgical Aesthetics

Stem Cells & Exosomes

Developments in the field of regenerative medicine in recent years have given rise to new approaches to skin renewal and tissue repair. Among these treatments, stem cell technologies, exosomes and human-derived cellular products stand out. The aim is to support the skin's natural renewal processes, improve tissue quality and help reduce the appearance of age-related changes.

Approach
Regenerative
Treatment
After clinical assessment
Regulation
Varies by country
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What Are Stem Cells?

Cells that can differentiate and renew themselves.

Developments in the field of regenerative medicine in recent years have given rise to new approaches to skin renewal and tissue repair. Among these treatments, stem cell technologies, exosomes and human-derived cellular products stand out.

The aim is to support the skin's natural renewal processes, improve tissue quality and help reduce the appearance of age-related changes.

Potential Areas of Use for Exosomes

  • Supporting skin quality
  • Promoting skin renewal
  • Hair treatments
  • Supporting tissue healing processes

Exosome technologies are still one of the fields in which scientific research is ongoing, and their forms of use may be subject to different regulations depending on the country.

Biological Targets

The areas targeted by regenerative approaches.

Regenerative protocols aim to support the body's own renewal processes. The headings below summarise the biological mechanisms these approaches target; definitive results may vary according to the individual, the protocol and the clinical assessment.

— 01

Tissue repair

The aim is to support the tissue repair mechanisms beneath the skin through the natural signalling of the cells.

— 02

Cellular renewal

Support of the cellular renewal cycle, which slows with age, through biological signals is the subject of ongoing research.

— 03

Healing processes

The aim is to support the skin's healing processes; the clinical effect may vary according to the individual and the condition of the skin.

— 04

Biological balance

Research into maintaining the mechanisms of biological balance is an important heading within regenerative medicine.

— 05

Skin quality

The aim is to contribute to improving skin quality and to reduce the appearance of age-related changes.

Three Approaches

The same framework, three different biologies.

Stem cells, exosomes and allogeneic fibroblasts — three different branches of regenerative medicine. All of them work through cellular communication and tissue renewal, but their contents, mechanisms and clinical frameworks of use differ from one another. A summary definition of each is given below.

i

Stem Cells

Living cell · repair capacity
Special cells found naturally in the human body that can differentiate into different cell types. In regenerative medicine treatments, intensive research is being carried out on the biological signals and growth factors they secrete.
  • Contains living cells
  • Has the capacity for self-renewal
  • May play a role in tissue repair
ii

Exosomes

Messenger vesicle · carrier of communication
Microscopic messenger vesicles secreted naturally by cells. They carry proteins, growth factors, peptides and RNA molecules; they mediate communication between cells. Exosome technologies are still a field in which scientific research is ongoing.
  • They are not cells
  • They are messenger vesicles secreted by cells
  • They take part in communication between cells
iii

Allogeneic Fibroblasts

Advanced biotechnology product
One of the new-generation biological products used in regenerative medicine treatments, among the human-derived cellular biotechnological products. It aims to support cellular communication and tissue renewal processes.
  • Belongs to the group of human-derived biological regenerative products
  • Aims to support cellular signalling mechanisms
  • May cover advanced technology products
iv

Human-derived cellular products — the shared framework

Regulatory note
Human-derived cellular products are prepared by putting biological materials obtained from human tissues through special processes. Their aims are to support cellular communication, stimulate tissue renewal mechanisms, contribute to improving skin quality and support regenerative processes. The areas of use and legal regulation of these products may differ from country to country; the potential areas of use of exosome technologies (skin quality, skin renewal, hair treatments, tissue healing) are also assessed within the same regulatory framework.
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